T-Hawk field / laboratory platform
A discovery platform that starts in the desert at night and ends with a molecule that can actually be manufactured.
Venom Library: Collection Protocols
Permitted seasonal field collection across five arthropod orders, with organism-, organ-, and venom-level protocols developed for each lineage. Flash-freeze handling where autoproteolysis is a known risk.
Peptide Identification: Genomics / Proteomics
Intelligent genomic sequencing paired with targeted LC-MS/MS proteomics performed by skilled institutional partners captures a complete survey of the active venom peptide components.
Target Validation: Ion Channels / Antimicrobial HTS
Candidate peptides are screened against ion channel panels and antimicrobial high-throughput assays to confirm activity, selectivity, and subtype sparing.
Lead Optimization: Single Cell / Patch Clamp
Automated and manual patch clamp electrophysiology at specialist CROs establishes potency and selectivity against human channel subtypes.
Development Candidates: Manufacturing Feasibility
Every candidate is tested against a production route, recombinant expression or synthesis, before it is called a development candidate. Manufacturability is a selection criterion, not a downstream surprise.
What T-Hawk owns
- Collection range access, seasonal timing, and species-specific field protocols.
- The organism / peptide / mechanism database underlying candidate prioritization.
- Multi-dimensional scoring that ranks candidates on potency, selectivity, safety, manufacturability, and freedom to operate, before spend is committed.
What partners run
- Genomics and Proteomics at institutional analytics partners.
- Automated patch clamp ion channel validation at specialist CROs.
- Peptide production: recombinant expression for novel sequences, synthesis for known references.
Capital is spent on assets and IP rather than on instruments and square footage.